estradiol cypionate造句

• The side effects of estradiol cypionate are the same as those of estradiol.
• Examples include testosterone cypionate, estradiol cypionate, hydrocortisone cypionate, and oxabolone cypionate.
• The medical uses of estradiol cypionate are the same as those of estradiol and other estrogens.
• Along with estradiol cypionate, estradiol valerate is one of the most widely used esters of estradiol.
• Along with estradiol valerate, estradiol cypionate is one of the most widely used esters of estradiol.
• In regards to the latter, estradiol cypionate is available as a combined injectable contraceptive in combination with medroxyprogesterone acetate.
• This is because estradiol cypionate has a more extensive fatty acid chain and in relation to this is comparatively more lipophilic.
• They have been referred to as the " endogenous counterparts of the synthetic esters of estrogens " like estradiol valerate and estradiol cypionate.
• The terminal half-life of intramuscularly administered estradiol cypionate in oil ( as estradiol ) has been reported to be approximately 8 days.
• Estradiol, mainly as esters including estradiol valerate, estradiol cypionate, and estradiol enanthate, is the exclusive estrogen used in combined injectable contraceptives.
• The slow release of estradiol cypionate is caused by the increased lipophilicity of the drug, which in turn is due to its long fatty acid cypionic acid ester moiety.
• Estradiol was formerly available as estradiol cypionate in combination with medroxyprogesterone acetate as a once-monthly intramuscular combined injectable contraceptive ( Lunelle ), but this product was discontinued.
• However, estradiol benzoate is now little used, having largely been superseded by longer-acting esters of estradiol like estradiol valerate and estradiol cypionate that require less frequent administration.
• Estradiol, in an ester prodrug form such as estradiol valerate or estradiol cypionate, can be administered by intramuscular injection, via which a long-lasting depot effect occurs.
• "' Lunelle "'and "'Cyclofem "'are combined injectable contraceptives containing 5 mg estradiol cypionate and 25 mg medroxyprogesterone acetate for once-monthly intramuscular administration.
• Upon intramuscular injection of estradiol cypionate in an oil solution, the solvent ( i . e ., oil ) is absorbed, and a primary microcrystalline depot is formed within the muscle at the site of injection.
• A combination of estradiol cypionate and testosterone cypionate ( Depo-Testadiol ) and a combination of estradiol valerate and testosterone enanthate ( Ditate-DS ) were previously marketed in the U . S . but have been discontinued as well.
• Testosterone cypionate and testosterone enanthate were formerly available in combination with estradiol cypionate and estradiol valerate, respectively, under the brand names Depo-Testadiol and Ditate-DS, respectively, as oil solutions for intramuscular injection, but these formulations have been discontinued.
• A combination of testosterone cypionate and estradiol cypionate ( brand name Depo-Testadiol ) and a combination of testosterone enanthate and estradiol valerate ( brand name Ditate-DS ) were also formerly available as oil solutions for intramuscular injection, but these formulations have been discontinued.
• A single intramuscular injection of 5 mg estradiol cypionate has been found to result in peak circulating concentrations of 338 pg / mL estradiol and 145 pg / mL estrone, which occurred at about 4 and 5 days post-injection, respectively ( see right table ).